CALL FOR PAPERS Novel Therapeutics in Renal Disease Chronic bilateral renal denervation attenuates renal injury in a transgenic rat model of diabetic nephropathy
نویسندگان
چکیده
Yimin Yao, Ingrid C. Fomison-Nurse, Joanne C. Harrison, Robert J. Walker, Gerard Davis, and Ivan A. Sammut Department of Pharmacology, University of Otago, Dunedin, New Zealand; Department of Medicine, University of Otago, Dunedin, New Zealand; Department of Physiology, University of Otago, Dunedin, New Zealand; and Australian School of Advanced Medicine, Macquarie University, New South Wales, Australia
منابع مشابه
Chronic bilateral renal denervation attenuates renal injury in a transgenic rat model of diabetic nephropathy.
Bilateral renal denervation (BRD) has been shown to reduce hypertension and improve renal function in both human and experimental studies. We hypothesized that chronic intervention with BRD may also attenuate renal injury and fibrosis in diabetic nephropathy. This hypothesis was examined in a female streptozotocin-induced diabetic (mRen-2)27 rat (TGR) shown to capture the cardinal features of h...
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تاریخ انتشار 2014